Search results for "Curve shape"

showing 1 items of 1 documents

2020

Background. Anticoagulant therapy, the cornerstone treatment in acute venous thromboembolism (VTE), strongly impacts thrombin generation (TG). Until now, the appearance of the TG curve in platelet rich plasma (PRP) from patients with acute VTE has not been investigated. Methods. We analyzed the shape of TG curves measured in PARP of 180 acute VTE patients. Results. Normal shape of TG curves was observed in 110 patients, 50 patients showed no TG and 20 patients showed biphasic TG curve. The linear regression analysis, adjusted for age, sex, VTE clinical phenotypes and therapy showed that the appearance of biphasic curves is significantly associated with female sex, presence of cancer and the…

medicine.medical_specialtymedicine.drug_mechanism_of_actionbusiness.industryFactor Xa InhibitorCancerGeneral Medicinemedicine.diseaseGastroenterologyThrombin generationPlatelet-rich plasmaInternal medicinemedicineClinical significanceCurve shapePlateletcardiovascular diseasesbusinessVenous thromboembolismJournal of Clinical Medicine

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PEPhysical Sciences and Engineering
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LSLife Sciences
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